Nras

Predicted to enable GDP binding activity; GTP binding activity; and GTPase activity. Involved in positive regulation of angiogenesis. Acts upstream of or within several processes, including T cell receptor signaling pathway; defense response to protozoan; and positive regulation of type II interferon production. Located in membrane. Is expressed in several structures, including alimentary system; brain; cardiovascular system; eye; and genitourinary system. Used to study skin melanoma. Human ortholog(s) of this gene implicated in several diseases, including Noonan syndrome 6; autoimmune lymphoproliferative syndrome type 4; endocrine gland cancer (multiple); hematologic cancer (multiple); and reproductive organ cancer (multiple). Orthologous to human NRAS (NRAS proto-oncogene, GTPase). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Nras often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Nras gene in mouse plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the mouse Nras gene, providing context for its role in the cell.