Carmil3 Gene Summary [Mouse]
Involved in regulation of postsynapse assembly. Is active in glutamatergic synapse and postsynapse. Is expressed in central nervous system; dorsal root ganglion; extraembryonic component; and olfactory epithelium. Orthologous to human CARMIL3 (capping protein regulator and myosin 1 linker 3). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Nonsense Mediated Decay |
| Official Symbol | Carmil3 |
| Official Name | capping protein regulator and myosin 1 linker 3 [Source:MGI Symbol;Acc:MGI:2448573] |
| Ensembl ID | ENSMUSG00000022211 |
| Bio databases IDs | |
| Aliases | capping protein regulator and myosin 1 linker 3 |
| Synonyms | C14orf121, capping protein regulator and myosin 1 linker 3, crml-1, LOC90668, LRRC16B, mFLJ00240 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Carmil3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Carmil pleckstrin homology domain
- CARMIL C-terminus
- protein phosphatase 1 regulatory subunit 42
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- glutaminergic synapse
- Cytoplasm
- postsynaptic region
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Carmil3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cell migration
- regulation of Arp2/3 complex-mediated actin nucleation
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- plasma membrane
- lamellipodium