Csmd3 Gene Summary [Mouse]
Involved in regulation of dendrite development. Located in plasma membrane. Is expressed in brain; heart ventricle; and lens. Orthologous to human CSMD3 (CUB and Sushi multiple domains 3). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Csmd3 |
| Official Name | CUB and Sushi multiple domains 3 [Source:MGI Symbol;Acc:MGI:2386403] |
| Ensembl ID | ENSMUSG00000022311 |
| Bio databases IDs | |
| Aliases | CUB and Sushi multiple domains 3 |
| Synonyms | 4930500N14RIK, CUB and Sushi multiple domains 3, LOC108351600, mKIAA1894 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Csmd3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- CCP
- CUB
- enzyme
- Sushi repeat (SCR repeat)
- SUSHI repeat
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- major depression
- epithelial cancer
- liver cancer
- focal cortical dysplasia of Taylor
- insomnia
- myelin oligodendrocyte glycoprotein induced experimental autoimmune encephalomyelitis
- idiopathic scoliosis
- hepatocellular carcinoma
- insulin-dependent diabetes mellitus
- renal clear cell adenocarcinoma
role in cell
- proliferation
- development
- abnormal morphology
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cellular membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Csmd3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of dendrite development
Cellular Component
Where in the cell the gene product is active
- plasma membrane