AABR07057765.1 Gene Summary [Rat]

Predicted to enable serine-type endopeptidase activity. Predicted to be involved in regulation of dendrite development. Predicted to be located in plasma membrane. Predicted to be active in extracellular space. Orthologous to human CSMD3 (CUB and Sushi multiple domains 3). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Processed Transcript
Official Symbol
AABR07057765.1
Official Name
CUB and Sushi multiple domains 3 [Source:NCBI gene;Acc:314942]
Ensembl ID
ENSRNOG00000004937
Bio databases IDs NCBI: 314942 Ensembl: ENSRNOG00000004937
Aliases CUB and Sushi multiple domains 3
Synonyms 4930500N14RIK, CUB and Sushi multiple domains 3, LOC108351600, mKIAA1894
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Aabr07057765.1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • CCP
  • CUB
  • enzyme
  • Sushi repeat (SCR repeat)
  • SUSHI repeat

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • major depression
  • epithelial cancer
  • liver cancer
  • focal cortical dysplasia of Taylor
  • insomnia
  • myelin oligodendrocyte glycoprotein induced experimental autoimmune encephalomyelitis
  • idiopathic scoliosis
  • hepatocellular carcinoma
  • insulin-dependent diabetes mellitus
  • renal clear cell adenocarcinoma
regulated by
role in cell
  • proliferation
  • development
  • abnormal morphology

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane
  • cellular membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Aabr07057765.1 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • regulation of dendrite development

Cellular Component

Where in the cell the gene product is active
  • plasma membrane