Kansl2 Gene Summary [Mouse]
Predicted to be involved in positive regulation of DNA-templated transcription. Part of NSL complex. Is active in mitochondrion. Is expressed in nervous system and retina nuclear layer. Orthologous to human KANSL2 (KAT8 regulatory NSL complex subunit 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Kansl2 |
| Official Name | KAT8 regulatory NSL complex subunit 2 [Source:MGI Symbol;Acc:MGI:1916862] |
| Ensembl ID | ENSMUSG00000022992 |
| Bio databases IDs | |
| Aliases | KAT8 regulatory NSL complex subunit 2 |
| Synonyms | 2310037I24Rik, B930009D17, C12orf41, KAT8 regulatory NSL complex subunit 2, LOC103690317, NSL2, RGD1303127 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Kansl2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Potential DNA-binding domain
- protein binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- actin cytoskeleton
- Plasma Membrane
- Mitochondria
- cytosol
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Kansl2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- positive regulation of transcription, DNA-dependent
- chromatin organization
Cellular Component
Where in the cell the gene product is active
- mitochondrion
- actin cytoskeleton
- cytosol
- NSL complex
- plasma membrane
- nucleoplasm
- histone acetyltransferase complex
Molecular Function
What the gene product does at the molecular level
- protein binding