Lrrc45 Gene Summary [Mouse]

Predicted to be located in cytosol and nucleoplasm. Predicted to be active in centrosome and plasma membrane. Is expressed in cerebral cortex ventricular layer and cortical plate. Orthologous to human LRRC45 (leucine rich repeat containing 45). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Lrrc45
Official Name
leucine rich repeat containing 45 [Source:MGI Symbol;Acc:MGI:2387183]
Ensembl ID
ENSMUSG00000025145
Bio databases IDs NCBI: 217366 Ensembl: ENSMUSG00000025145
Aliases leucine rich repeat containing 45
Synonyms leucine rich repeat containing 45, LOC103689934
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Lrrc45 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Leucine rich repeat
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • neuroblastoma
  • neuroblastoma formation

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Plasma Membrane
  • basal bodies
  • centrosome
  • cytosol
  • nucleoplasm

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Lrrc45 gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • centrosome
  • cytosol
  • plasma membrane
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.