Cbr2 Gene Summary [Mouse]
Enables carbonyl reductase (NADPH) activity and identical protein binding activity. Predicted to be involved in glucose metabolic process and xylulose metabolic process. Located in mitochondrion. Is expressed in alimentary system; heart; nervous system; nose; and respiratory system. [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Cbr2 |
| Official Name | carbonyl reductase 2 [Source:MGI Symbol;Acc:MGI:107200] |
| Ensembl ID | ENSMUSG00000025150 |
| Bio databases IDs | |
| Aliases | carbonyl reductase 2 |
| Synonyms | carbonyl reductase 2, MLCR |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Cbr2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Rossmann-fold NAD(P)(+)-binding proteins
- sepiapterin reductase
- SDR family mycofactocin-dependent oxidoreductase
- NAD dependent epimerase/dehydratase family
- pteridine reductase
- enzyme
- protein binding
- Enoyl-(Acyl carrier protein) reductase
- short chain dehydrogenase
- identical protein binding
- carbonyl reductase (NADPH)
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- mitochondrial matrix