Acbd3 Gene Summary [Mouse]
Predicted to enable protein kinase A regulatory subunit binding activity. Predicted to be involved in steroid biosynthetic process. Predicted to be located in Golgi apparatus. Predicted to be active in Golgi membrane. Is expressed in brain; genitourinary system; gut; and lung. Orthologous to human ACBD3 (acyl-CoA binding domain containing 3). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Acbd3 |
| Official Name | acyl-Coenzyme A binding domain containing 3 [Source:MGI Symbol;Acc:MGI:2181074] |
| Ensembl ID | ENSMUSG00000026499 |
| Bio databases IDs | |
| Aliases | acyl-Coenzyme A binding domain containing 3 |
| Synonyms | 8430407O11Rik, acyl-CoA binding domain containing 3, acyl-Coenzyme A binding domain containing 3, D1Ertd10e, DAP, GCP60, GOCAP1, GOLPH1, PAP7 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Acbd3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein kinase A binding
- protein binding
- Golgi-dynamics membrane-trafficking
- GPCR-chaperone
- ACBP
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- epithelial cancer
- head and neck cancer
- esophageal cancer
- renal clear cell cancer
- lung squamous cell carcinoma
- hepatocellular carcinoma
- breast cancer
- renal clear cell adenocarcinoma
- lung adenocarcinoma
- lung adenocarcinoma formation
regulated by
- VPR
- OSW-1
- ASPSCR1
role in cell
- expression in
- disassembly
- retention in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Golgi-enriched fraction
- cellular membrane
- Golgi Apparatus
- cytosol
- Golgi membrane
- Golgi stacks
- brush border membrane vesicles
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Acbd3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- steroid biosynthetic process
Cellular Component
Where in the cell the gene product is active
- mitochondrion
- membrane
- Golgi membrane
- Golgi apparatus
Molecular Function
What the gene product does at the molecular level
- protein binding
- fatty-acyl-CoA binding
- protein kinase A regulatory subunit binding