Pacc1 Gene Summary [Mouse]
Enables pH-gated chloride channel activity. Involved in chloride transport. Predicted to be located in plasma membrane. Predicted to be part of chloride channel complex. Orthologous to human PACC1 (proton activated chloride channel 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Pacc1 |
| Official Name | proton activated chloride channel 1 [Source:MGI Symbol;Acc:MGI:1914200] |
| Ensembl ID | ENSMUSG00000026627 |
| Bio databases IDs | |
| Aliases | proton activated chloride channel 1 |
| Synonyms | 2310028N02Rik, ASOR, C1orf75, hPAC, hTMEM206, LOC55248, PAC, PAORAC, proton activated chloride channel 1, RGD1359339, TMEM206 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Pacc1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- anion channel
- TMEM206 protein family
- chloride channel
- ligand-gated ion channel
- protein binding
- ion channel
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Pacc1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- chloride transport
Cellular Component
Where in the cell the gene product is active
- chloride channel complex
- plasma membrane
- cell surface
Molecular Function
What the gene product does at the molecular level
- protein binding