Naxd Gene Summary [Mouse]
Predicted to enable ATP-dependent NAD(P)H-hydrate dehydratase activity. Predicted to be involved in metabolite repair. Located in cytosol; endoplasmic reticulum; and mitochondrion. Is expressed in metanephros. Orthologous to human NAXD (NAD(P)HX dehydratase). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Naxd |
| Official Name | NAD(P)HX dehydratase [Source:MGI Symbol;Acc:MGI:1913353] |
| Ensembl ID | ENSMUSG00000031505 |
| Bio databases IDs | |
| Aliases | NAD(P)HX dehydratase |
| Synonyms | 0710008K08Rik, 2810407E01Rik, CARKD, LP3298, NAD(P)HX dehydratase, PEBEL2, RGD1562691 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Naxd often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- ribokinase_pfkB_like
- enzyme
- protein binding
- ATP-dependent H4NAD(P)OH dehydratase
Pathways
Biological processes and signaling networks where the Naxd gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Endoplasmic Reticulum
- Mitochondria
- cytosol
- mitochondrial matrix
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Naxd gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- NAD biosynthesis via nicotinamide riboside salvage pathway
Cellular Component
Where in the cell the gene product is active
- mitochondrial matrix
Molecular Function
What the gene product does at the molecular level
- ATP binding
- protein binding
- ATP-dependent NAD(P)H-hydrate dehydratase activity