Sypl2 Gene Summary [Mouse]
Acts upstream of or within T-tubule organization; heart development; and intracellular calcium ion homeostasis. Predicted to be located in membrane and synaptic vesicle. Predicted to be active in synaptic vesicle membrane. Is expressed in heart ventricle and skeletal muscle. Orthologous to human SYPL2 (synaptophysin like 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Sypl2 |
| Official Name | synaptophysin-like 2 [Source:MGI Symbol;Acc:MGI:1328311] |
| Ensembl ID | ENSMUSG00000027887 |
| Bio databases IDs | |
| Aliases | synaptophysin-like 2 |
| Synonyms | MG29, synaptophysin-like 2 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Sypl2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Membrane-associating domain
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- cellular membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Sypl2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- heart development
- T-tubule organization
- substantia nigra development
- cellular calcium ion homeostasis
Cellular Component
Where in the cell the gene product is active
- synaptic vesicle membrane