SYPL2 Gene Summary [Human]
Involved in substantia nigra development. Predicted to be integral component of membrane. Predicted to be active in synaptic vesicle membrane. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | SYPL2 |
| Official Name | synaptophysin like 2 [Source:HGNC Symbol;Acc:HGNC:27638] |
| Ensembl ID | ENSG00000143028 |
| Bio databases IDs | |
| Aliases | synaptophysin like 2, mitsugumin-29 |
| Synonyms | MG29, synaptophysin-like 2 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human SYPL2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Membrane-associating domain
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- cellular membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human SYPL2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- heart development
- T-tubule organization
- substantia nigra development
- cellular calcium ion homeostasis
Cellular Component
Where in the cell the gene product is active
- synaptic vesicle membrane