Syngr2 Gene Summary [Mouse]
Predicted to be involved in regulated exocytosis and synaptic vesicle membrane organization. Predicted to act upstream of or within protein targeting. Located in synaptic vesicle. Is expressed in several structures, including brain; genitourinary system; liver; lung; and spleen. Orthologous to human SYNGR2 (synaptogyrin 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Syngr2 |
| Official Name | synaptogyrin 2 [Source:MGI Symbol;Acc:MGI:1328324] |
| Ensembl ID | ENSMUSG00000048277 |
| Bio databases IDs | |
| Aliases | synaptogyrin 2 |
| Synonyms | cellugyrin, Clast2, synaptogyrin 2 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Syngr2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Membrane-associating domain
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- lung adenocarcinoma
- lung adenocarcinoma formation
- vitiligo
- lung carcinoma
- lung carcinoma process
- lichen planus
regulates
- GH1
- SYP
role in cell
- cell death
- number
- replication in
- organization
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- synaptic vesicle membrane
- cellular membrane
- synaptic vesicles
- synaptic-like microvesicles
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Syngr2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- synaptic vesicle membrane organization
- regulated secretory pathway
Cellular Component
Where in the cell the gene product is active
- lipid particle
- extracellular vesicular exosome
- membrane
- neuromuscular junction
- synaptic vesicle membrane
Molecular Function
What the gene product does at the molecular level
- protein binding