Spocd1 Gene Summary [Mouse]
Enables protein-macromolecule adaptor activity. Involved in spermatogenesis; transposable element silencing by piRNA-mediated DNA methylation; and transposable element silencing by piRNA-mediated heterochromatin formation. Located in nucleus. Is expressed in germ cell of testis. Orthologous to human SPOCD1 (SPOC domain containing 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Spocd1 |
| Official Name | SPOC domain containing 1 [Source:MGI Symbol;Acc:MGI:3652045] |
| Ensembl ID | ENSMUSG00000028784 |
| Bio databases IDs | |
| Aliases | SPOC domain containing 1 |
| Synonyms | FLJ25348, IMAGE:4299322, PPP1R146, RGD1560989, Spocd1-ps1, SPOC domain containing 1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Spocd1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- SPOC (Spen paralog and ortholog C-terminal) domain superfamily
- Transcription factor S-II (TFIIS), central domain
- SPOC domain
- protein binding activity, bridging
- protein binding
- Transcription factor S-II M domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Spocd1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- transcription, DNA-dependent
- spermatogenesis
- cell differentiation
Cellular Component
Where in the cell the gene product is active
- nucleus
- chromosome
Molecular Function
What the gene product does at the molecular level
- protein binding