SPOCD1 Gene Summary [Human]

This gene encodes a protein that belongs to the TFIIS family of transcription factors. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

Details

Type
Protein Coding
Official Symbol
SPOCD1
Official Name
SPOC domain containing 1 [Source:HGNC Symbol;Acc:HGNC:26338]
Ensembl ID
ENSG00000134668
Bio databases IDs NCBI: 90853 Ensembl: ENSG00000134668
Aliases SPOC domain containing 1, protein phosphatase 1, regulatory subunit 146
Synonyms FLJ25348, IMAGE:4299322, PPP1R146, RGD1560989, Spocd1-ps1, SPOC domain containing 1
Species
Human, Homo sapiens
OrthologiesMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human SPOCD1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • SPOC (Spen paralog and ortholog C-terminal) domain superfamily
  • Transcription factor S-II (TFIIS), central domain
  • SPOC domain
  • protein binding activity, bridging
  • protein binding
  • Transcription factor S-II M domain

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • diabetic nephropathy
  • preeclampsia
  • insulin resistance
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • nucleoplasm

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human SPOCD1 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • transcription, DNA-dependent
  • spermatogenesis
  • cell differentiation

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • chromosome

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

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