Gpn2 Gene Summary [Mouse]
Predicted to enable GTPase activity. Is expressed in collecting duct; liver; renal calyx; and ureter. Orthologous to human GPN2 (GPN-loop GTPase 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Gpn2 |
| Official Name | GPN-loop GTPase 2 [Source:MGI Symbol;Acc:MGI:2140368] |
| Ensembl ID | ENSMUSG00000028848 |
| Bio databases IDs | |
| Aliases | GPN-loop GTPase 2 |
| Synonyms | ATPBD1B, GPN-loop GTPase 2, RGD1311749 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Gpn2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
- P-loop containing Nucleoside Triphosphate Hydrolases
- Conserved hypothetical ATP binding protein
- AAA domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Gpn2 gene, providing context for its role in the cell.
Molecular Function
What the gene product does at the molecular level
- GTP binding
- protein binding
- GTPase activity