Crybb3 Gene Summary [Mouse]
Predicted to be a structural constituent of eye lens. Predicted to be involved in lens development in camera-type eye and visual perception. Is expressed in eye; gut; and male reproductive gland or organ. Human ortholog(s) of this gene implicated in cataract 22 multiple types. Orthologous to human CRYBB3 (crystallin beta B3). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Crybb3 |
| Official Name | crystallin, beta B3 [Source:MGI Symbol;Acc:MGI:102717] |
| Ensembl ID | ENSMUSG00000029352 |
| Bio databases IDs | |
| Aliases | crystallin, beta B3 |
| Synonyms | beta B3 CRYSTALLIN, CATCN2, CRYB3, crystallin beta B3, crystallin, beta B3, crystallin β B3, crystallin, β B3, CTRCT22, β B3 CRYSTALLIN |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Crybb3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- structural constituent of eye lens
- protein binding
- Beta/Gamma crystallin
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Crybb3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- visual perception
- lens development in camera-type eye
Molecular Function
What the gene product does at the molecular level
- protein binding
- structural constituent of eye lens