Tmed10

Predicted to enable protein transmembrane transporter activity and syntaxin binding activity. Involved in several processes, including positive regulation of interleukin-1 production; positive regulation of protein secretion; and vesicle targeting, to, from or within Golgi. Acts upstream of or within negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process. Located in zymogen granule membrane. Part of gamma-secretase complex. Is expressed in several structures, including alimentary system; central nervous system; eye; genitourinary system; and hemolymphoid system gland. Orthologous to human TMED10 (transmembrane p24 trafficking protein 10). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Tmed10 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the mouse Tmed10 gene, providing context for its role in the cell.