Actbl2 Gene Summary [Mouse]
Predicted to enable protein kinase binding activity. Predicted to be a structural constituent of postsynaptic actin cytoskeleton. Predicted to be involved in axonogenesis and cell motility. Is active in glutamatergic synapse. Orthologous to human ACTBL2 (actin beta like 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Actbl2 |
| Official Name | actin, beta-like 2 [Source:MGI Symbol;Acc:MGI:2444552] |
| Ensembl ID | ENSMUSG00000055194 |
| Bio databases IDs | |
| Aliases | actin, beta-like 2 |
| Synonyms | 4732495G21Rik, ACT, actin beta like 2, actin, beta-like 2, actin β like 2, actin, β-like 2, LOC345651, RGD1309504 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Actbl2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Actin
- protein binding
- ASKHA_ATPase-like
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- glutaminergic synapse
- synapse
- exosomes
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Actbl2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cell motility
- axonogenesis
Cellular Component
Where in the cell the gene product is active
- extracellular space
- NuA4 histone acetyltransferase complex
- extracellular vesicular exosome
- cytoplasm
- membrane
- actin cytoskeleton
- actin filament
- axon
Molecular Function
What the gene product does at the molecular level
- ATP binding
- protein kinase binding
- protein binding