Ddx47 Gene Summary [Mouse]
Predicted to enable several functions, including ATP binding activity; ATP hydrolysis activity; and RNA helicase activity. Predicted to be involved in RNA splicing; extrinsic apoptotic signaling pathway via death domain receptors; and rRNA processing. Predicted to be located in nucleolus. Predicted to be active in nucleus. Is expressed in genitourinary system. Orthologous to human DDX47 (DEAD-box helicase 47). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Ddx47 |
| Official Name | DEAD box helicase 47 [Source:MGI Symbol;Acc:MGI:1915005] |
| Ensembl ID | ENSMUSG00000030204 |
| Bio databases IDs | |
| Aliases | DEAD box helicase 47 |
| Synonyms | 4930588A18Rik, DEAD-box helicase 47, E4-DBP, HQ0256, MSTP162, RRP3 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ddx47 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- helicase superfamily c-terminal domain
- DEAD/DEAH box helicase
- Type III restriction enzyme, res subunit
- N-terminal helicase domain of the DEAD-box helicase superfamily
- enzyme
- protein binding
- DEAD-like helicases superfamily
- Helicase conserved C-terminal domain
- P-loop containing Nucleoside Triphosphate Hydrolases
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nucleoplasm
- nucleoli
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Ddx47 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- RNA splicing
- mRNA processing
- rRNA processing
- induction of apoptosis via death domain receptors
Cellular Component
Where in the cell the gene product is active
- nucleus
- membrane
- nucleolus
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- ATPase activity
- ATP binding
- RNA binding
- protein binding
- RNA helicase activity