Cd209a Gene Summary [Mouse]
Enables D-mannose binding activity and carbohydrate derivative binding activity. Predicted to be involved in immune response. Predicted to act upstream of or within regulation of T cell proliferation. Located in cell surface. Human ortholog(s) of this gene implicated in Coronavirus infectious disease; aspergillosis; dengue disease (multiple); human immunodeficiency virus infectious disease (multiple); and tuberculosis (multiple). Orthologous to human CD209 (CD209 molecule). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Cd209a |
| Official Name | CD209a antigen [Source:MGI Symbol;Acc:MGI:2157942] |
| Ensembl ID | ENSMUSG00000031494 |
| Bio databases IDs | |
| Aliases | CD209a antigen |
| Synonyms | CD209, CD209a antigen, CDSIGN, CIRE, DC-SIGN, DC-SIGN1, SIGN-R1, SIGNR5 |
| Species | Mouse, Mus musculus |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Cd209a often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- calcium-dependent protein binding
- extracellular domain
- binding protein
- viral receptor
- C-type lectin (CTL)/C-type lectin-like (CTLD) domain
- cytoplasmic domain
- carbohydrate recognition domain
- transmembrane domain
- Lectin C-type domain
- neck domain
- carbohydrate binding
- mannose binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
role in cell
- number
- production in
- proliferation
- differentiation
- invasion by
- induction
- binding
- killing
- phagocytosis by
- killing in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cell surface
- cellular membrane
- plasma membrane extracellular face