Ceacam1 Gene Summary [Mouse]
Enables Toll-like receptor binding activity; granulocyte colony-stimulating factor receptor binding activity; and protein tyrosine kinase binding activity. Involved in several processes, including common myeloid progenitor cell proliferation; granulocyte colony-stimulating factor signaling pathway; and negative regulation of metabolic process. Acts upstream of or within several processes, including negative regulation of T cell proliferation; negative regulation of bone resorption; and negative regulation of osteoclast differentiation. Located in ciliary membrane and external side of plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; extraembryonic component; genitourinary system; and skeleton. Orthologous to human CEACAM1 (CEA cell adhesion molecule 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Ceacam1 |
| Official Name | carcinoembryonic antigen-related cell adhesion molecule 1 [Source:MGI Symbol;Acc:MGI:1347245] |
| Ensembl ID | ENSMUSG00000074272 |
| Bio databases IDs | |
| Aliases | carcinoembryonic antigen-related cell adhesion molecule 1 |
| Synonyms | bb-1, Bgp, Bgp1, Bgp2, Bgpd, Cc1, C-CAM, CD66a, Cea-1, Cea-7, Ceacam1, Ceacam2, Ceacam2-L, CEA cell adhesion molecule 1, CEA cell adhesion molecule 2, Hv-2, mCEA1, Mhv-1, MHVR, MHVR1, Mhv-receptor, mmCGM1, mmCGM1a, mmCGM2, pp120 |
| Species | Mouse, Mus musculus |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ceacam1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein dimerization
- granulocyte colony-stimulating factor receptor binding
- identical protein binding
- T-cell surface glycoprotein CD3 delta chain
- cytoskeletal protein binding
- cytoplasmic domain
- actin binding
- Immunoglobulin like
- immunoglobulin-like protein domain
- bile acid transporter
- transmembrane receptor
- Immunoglobulin V-set domain
- lipid binding
- protein kinase binding
- calmodulin binding
- immunoglobulin domain
- protein phosphatase binding
- Immunoglobulin I-set domain
- protein binding
- receptor binding
- phosphatidylinositol binding
- binding protein
- kinase binding
- Transmembrane domain of Ephrin Receptor A1 Protein Tyrosine Kinase
- protein homodimerization
- protein heterodimerization
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- infection
- neoplasia
- metastasis
- insulin resistance
- colitis
- microgliosis
- hyperphagia
- obesity
- infection by murine hepatitis virus
- infection by coronavirus
role in cell
- expression in
- function
- proliferation
- differentiation
- migration
- tyrosine phosphorylation in
- aggregation
- colony formation
- adhesion
- fusion
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- membrane fraction
- cell junction
- cilia
- cell surface
- Extracellular Space
- intracellular space
- microvesicles
- cellular membrane
- intercellular junctions
- cell-cell contacts
- plasma membrane extracellular face
- apical membrane
- basolateral membrane
- basal membrane
- lateral plasma membrane
- brush border
- cell-cell adherens junctions