Tti2 Gene Summary [Mouse]
Predicted to be part of TTT Hsp90 cochaperone complex. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 39. Orthologous to human TTI2 (TELO2 interacting protein 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Tti2 |
| Official Name | TELO2 interacting protein 2 [Source:MGI Symbol;Acc:MGI:2384576] |
| Ensembl ID | ENSMUSG00000031577 |
| Bio databases IDs | |
| Aliases | TELO2 interacting protein 2 |
| Synonyms | C8orf41, MRT39, RGD1310414, TELO2 interacting protein 2 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Tti2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Tti2 family
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Tti2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- positive regulation of DNA damage checkpoint
- protein stabilization
Cellular Component
Where in the cell the gene product is active
- nucleus