Gpr84 Gene Summary [Mouse]
Predicted to enable urotensin II receptor activity. Predicted to be involved in neuropeptide signaling pathway. Predicted to be part of receptor complex. Predicted to be active in plasma membrane. Is expressed in adrenal gland; genitourinary system; gut; skin; and thoracic segment skeleton. Orthologous to human GPR84 (G protein-coupled receptor 84). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Gpr84 |
| Official Name | G protein-coupled receptor 84 [Source:MGI Symbol;Acc:MGI:1934129] |
| Ensembl ID | ENSMUSG00000063234 |
| Bio databases IDs | |
| Aliases | G protein-coupled receptor 84 |
| Synonyms | EX33, GPCR4, G protein-coupled receptor 84, LOC684132 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Gpr84 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- G-protein coupled receptor
- protein binding
- seven-transmembrane G protein-coupled receptor superfamily
Pathways
Biological processes and signaling networks where the Gpr84 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- hyperinsulinism
- mechanical hypersensitivity
- acute myeloid leukemia
- sepsis
- septic shock
- diminished ovarian reserve
- hypersensitive reaction
- Alzheimer disease
- chronic periodontal disease
role in cell
- expression in
- accumulation in
- activation in
- phosphorylation in
- quantity
- binding in
- function
- generation in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cellular membrane
- tertiary granule membrane
- specific granule membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Gpr84 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- neuropeptide signaling pathway
Cellular Component
Where in the cell the gene product is active
- receptor complex
- plasma membrane
- tertiary granule membrane
- specific granule membrane
Molecular Function
What the gene product does at the molecular level
- urotensin II receptor activity