Hhatl Gene Summary [Mouse]
Involved in negative regulation of N-terminal protein palmitoylation. Located in endoplasmic reticulum. Orthologous to human HHATL (hedgehog acyltransferase like). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Hhatl |
| Official Name | hedgehog acyltransferase-like [Source:MGI Symbol;Acc:MGI:1922020] |
| Ensembl ID | ENSMUSG00000032523 |
| Bio databases IDs | |
| Aliases | hedgehog acyltransferase-like |
| Synonyms | 1110011D13Rik, C3orf3, GUP1, hedgehog acyltransferase-like, MBOAT3, Mg56, MSTP002, OACT3, RGD1311911 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Hhatl often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- MBOAT, membrane-bound O-acyltransferase family
- enzyme
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- perinuclear region
- cellular membrane
- Endoplasmic Reticulum
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Hhatl gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- negative regulation of N-terminal protein palmitoylation
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum membrane
- perinuclear region of cytoplasm
- endoplasmic reticulum
Molecular Function
What the gene product does at the molecular level
- transferase activity, transferring acyl groups
- protein binding