Itgbl1 Gene Summary [Mouse]
Predicted to enable integrin binding activity. Predicted to be involved in several processes, including cell adhesion mediated by integrin; cell-matrix adhesion; and integrin-mediated signaling pathway. Predicted to be located in extracellular region. Predicted to be part of integrin complex. Predicted to be active in cell surface and focal adhesion. Is expressed in axial skeleton; brain; heart ventricle; meninges; and vibrissa. Orthologous to human ITGBL1 (integrin subunit beta like 1). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Itgbl1 |
| Official Name | integrin, beta-like 1 [Source:MGI Symbol;Acc:MGI:2443439] |
| Ensembl ID | ENSMUSG00000032925 |
| Bio databases IDs | |
| Aliases | integrin, beta-like 1 |
| Synonyms | B930011D01RIK, integrin, beta-like 1, integrin subunit beta like 1, integrin subunit β like 1, integrin, β-like 1, OSCP, TIED |
| Species | Mouse, Mus musculus |
| Orthologies |
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- metastasis
- aortic valve calcification
- osteolysis
- lung adenocarcinoma
- lung adenocarcinoma formation
- diabetic nephropathy
- head and neck squamous cell carcinoma
- head and neck squamous cell cancer
- dementia
- oral squamous cell carcinoma
role in cell
- migration
- expression in
- adhesion
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- Plasma Membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Itgbl1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cell-matrix adhesion
- cell adhesion mediated by integrin
- integrin-mediated signaling pathway
- cell adhesion
- cell migration
Cellular Component
Where in the cell the gene product is active
- focal adhesion
- extracellular region
- integrin complex
- plasma membrane
- cell surface
Molecular Function
What the gene product does at the molecular level
- integrin binding