Slc9c1 Gene Summary [Mouse]
Predicted to enable potassium:proton antiporter activity and sodium:proton antiporter activity. Acts upstream of or within flagellated sperm motility. Located in motile cilium. Orthologous to human SLC9C1 (solute carrier family 9 member C1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Slc9c1 |
| Official Name | solute carrier family 9, subfamily C (Na+-transporting carboxylic acid decarboxylase), member 1 [Source:MGI Symbol;Acc:MGI:2685456] |
| Ensembl ID | ENSMUSG00000033210 |
| Bio databases IDs | |
| Aliases | solute carrier family 9, subfamily C (Na+-transporting carboxylic acid decarboxylase), member 1 |
| Synonyms | Gm610, NHE, NHE-10, SLC9A10, sNHE, solute carrier family 9 member C1, solute carrier family 9, subfamily C (Na+-transporting carboxylic acid decarboxylase), member 1, sperm-NHE |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Slc9c1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Cyclic nucleotide-binding domain
- Sodium/hydrogen exchanger family
- protein binding
- ion channel
- Cyclic nucleotide-monophosphate binding domain
- CAP_ED
- sodium:hydrogen antiporter
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- motile cilia
- cilia
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Slc9c1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of intracellular pH
- potassium ion transmembrane transport
- sperm motility
- spermatogenesis
- cell differentiation
Cellular Component
Where in the cell the gene product is active
- motile cilium
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- ion channel activity
- potassium:hydrogen antiporter activity
- sodium:hydrogen antiporter activity