Neurl4 Gene Summary [Mouse]

Predicted to enable ubiquitin protein ligase activity. Acts upstream of or within mitochondrial DNA repair and spermatogenesis. Predicted to be located in centriole and mitochondrion. Orthologous to human NEURL4 (neuralized E3 ubiquitin protein ligase 4). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Processed Transcript
Official Symbol
Neurl4
Official Name
neuralized E3 ubiquitin protein ligase 4 [Source:MGI Symbol;Acc:MGI:1921092]
Ensembl ID
ENSMUSG00000047284
Bio databases IDs NCBI: 216860 Ensembl: ENSMUSG00000047284
Aliases neuralized E3 ubiquitin protein ligase 4
Synonyms BC023037, Gps2l, neuralized E3 ubiquitin protein ligase 4
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Neurl4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Neuralized
  • SPRY domain
  • protein binding
  • domain in neuralized proteins

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • systemic lupus erythematosus
  • autoimmune disease
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Unknown

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Neurl4 gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • cytoplasm
  • centriole

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.