Cdkl4 Gene Summary [Mouse]
Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in regulation of cell cycle. Predicted to be located in cytoplasm. Predicted to be active in nucleus. Is expressed in several structures, including alimentary system; central nervous system; reproductive system; respiratory system; and skeleton. Orthologous to human CDKL4 (cyclin dependent kinase like 4). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Cdkl4 |
| Official Name | cyclin-dependent kinase-like 4 [Source:MGI Symbol;Acc:MGI:3587025] |
| Ensembl ID | ENSMUSG00000033966 |
| Bio databases IDs | |
| Aliases | cyclin-dependent kinase-like 4 |
| Synonyms | AU067824, cyclin-dependent kinase-like 4, Gm942 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Cdkl4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- kinase
- Serine/Threonine protein kinases, catalytic domain
- Protein kinase (unclassified specificity)
- Protein Kinases, catalytic domain
- Protein tyrosine and serine/threonine kinase
- Protein kinase domain
- Tyrosine kinase, catalytic domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- Cytoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Cdkl4 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of cell cycle
- protein phosphorylation
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytoplasm
Molecular Function
What the gene product does at the molecular level
- ATP binding
- cyclin-dependent protein kinase activity
- protein serine/threonine kinase activity