Ifit1 Gene Summary [Mouse]

Predicted to enable RNA binding activity. Involved in response to virus. Acts upstream of or within cellular response to interferon-alpha; cellular response to interferon-beta; and response to bacterium. Located in cytoplasm. Is expressed in several structures, including alimentary system; cardiovascular system; eye; genitourinary system; and nervous system. Orthologous to several human genes including IFIT1B (interferon induced protein with tetratricopeptide repeats 1B). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Ifit1
Official Name
interferon-induced protein with tetratricopeptide repeats 1 [Source:MGI Symbol;Acc:MGI:99450]
Ensembl ID
ENSMUSG00000034459
Bio databases IDs NCBI: 15957 Ensembl: ENSMUSG00000034459
Aliases interferon-induced protein with tetratricopeptide repeats 1
Synonyms GARG-16, Ifi56, IFI-56K, Ifit1b, Ifitr-1, Interferon-induced protein with tetratricopeptide repeats, interferon-induced protein with tetratricopeptide repeats 1, ISG56, P56
Species
Mouse, Mus musculus
OrthologiesRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ifit1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Coatomer epsilon subunit
  • protein binding
  • RNA binding

Pathways

Biological processes and signaling networks where the Ifit1 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
disease
  • adenoma formation
  • Huntington disease
  • insulin-dependent diabetes mellitus
  • pituitary gland adenoma
  • head and neck neuroendocrine neoplasia
regulated by
regulates
role in cell
  • expression in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • cytosol

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.