Eif3c Gene Summary [Mouse]
Enables translation initiation factor activity. Involved in translational initiation. Part of eukaryotic translation initiation factor 3 complex, eIF3m. Is expressed in several structures, including central nervous system and retina. Orthologous to several human genes including EIF3C (eukaryotic translation initiation factor 3 subunit C). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Eif3c |
| Official Name | eukaryotic translation initiation factor 3, subunit C [Source:MGI Symbol;Acc:MGI:1926966] |
| Ensembl ID | ENSMUSG00000030738 |
| Bio databases IDs | |
| Aliases | eukaryotic translation initiation factor 3, subunit C |
| Synonyms | 3230401O13Rik, eIF3 p110, Eif3s8, eukaryotic translation initiation factor 3, subunit C, NipilA3, NIPIL(A3), Translation initiator factor 3s8, Xs, Xsl |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Eif3c often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- motif in proteasome subunits, Int-6, Nip-1 and TRIP-15
- ribosome binding
- translation initiation factor
- translation regulator
- Eukaryotic translation initiation factor 3 subunit 8 N-terminus
Pathways
Biological processes and signaling networks where the Eif3c gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown