Rfpl4 Gene Summary [Mouse]
Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in innate immune response and regulation of gene expression. Located in cytoplasm and female germ cell nucleus. Is expressed in bladder; central nervous system; and ureter. Orthologous to several human genes including RFPL4A (ret finger protein like 4A). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Rfpl4 |
| Official Name | ret finger protein-like 4 [Source:MGI Symbol;Acc:MGI:2149590] |
| Ensembl ID | ENSMUSG00000035191 |
| Bio databases IDs | |
| Aliases | ret finger protein-like 4 |
| Synonyms | D7Ertd486e, ret finger protein-like 4, ret finger protein-like 4A, Rfpl4a |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Rfpl4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- ring like zinc finger domain
- SPRY domain
- RFPL defining motif (RDM)
- zinc finger of C3HC4-type, RING
- RING finger (Really Interesting New Gene) domain and U-box domain superfamily
- protein binding
- B30.2 domain
- associated with SPRY domains
- SPRY-associated domain
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Nucleus