Gnptg Gene Summary [Mouse]
Enables protein homodimerization activity. Predicted to be involved in carbohydrate phosphorylation. Located in Golgi apparatus. Is expressed in several structures, including gonad; gut; hemolymphoid system gland; liver; and lung. Human ortholog(s) of this gene implicated in glycoproteinosis and mucolipidosis III gamma. Orthologous to human GNPTG (N-acetylglucosamine-1-phosphate transferase subunit gamma). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Gnptg |
| Official Name | N-acetylglucosamine-1-phosphotransferase, gamma subunit [Source:MGI Symbol;Acc:MGI:2147006] |
| Ensembl ID | ENSMUSG00000035521 |
| Bio databases IDs | |
| Aliases | N-acetylglucosamine-1-phosphotransferase, gamma subunit |
| Synonyms | 6430527N14Rik, A830081F19, AU067744, C16orf27, CAB56184, GNPTAG, LOC100505011, LP2537, Mdcp1, N-acetylglucosamine-1-phosphate transferase subunit gamma, N-acetylglucosamine-1-phosphate transferase subunit γ, N-acetylglucosamine-1-phosphotransferase, gamma subunit, N-acetylglucosamine-1-phosphotransferase, γ subunit, RJD9, Tce7 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Gnptg often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase
- Glucosidase II beta subunit-like protein
- protein homodimerization
- enzyme
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Extracellular Space
- Golgi Apparatus
- Golgi membrane
- plasma
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Gnptg gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- N-glycan processing to lysosome
- carbohydrate phosphorylation
Cellular Component
Where in the cell the gene product is active
- extracellular vesicular exosome
- UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase complex
- Golgi membrane
- Golgi apparatus
Molecular Function
What the gene product does at the molecular level
- UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity
- protein homodimerization activity
- protein binding