Mrps2 Gene Summary [Mouse]

Predicted to be a structural constituent of ribosome. Predicted to be involved in mitochondrial ribosome assembly and mitochondrial translation. Located in mitochondrion. Is expressed in several structures, including cerebral cortex; early conceptus; gonad; heart; and liver. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 36. Orthologous to human MRPS2 (mitochondrial ribosomal protein S2). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Mrps2
Official Name
mitochondrial ribosomal protein S2 [Source:MGI Symbol;Acc:MGI:2153089]
Ensembl ID
ENSMUSG00000035772
Bio databases IDs NCBI: 118451 Ensembl: ENSMUSG00000035772
Aliases mitochondrial ribosomal protein S2
Synonyms 1500019M10RIK, CGI-91, COXPD36, mitochondrial ribosomal protein S2, S2mt, uS2m
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Mrps2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • structural constituent of ribosome
  • Ribosomal protein S2
  • RPS2

Pathways

Biological processes and signaling networks where the Mrps2 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • combined oxidative phosphorylation deficiency 36
regulated by
  • TP53
  • TO-901317
  • beta-estradiol
  • valproic acid

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Mitochondria
  • mitochondrial matrix
  • mitochondrial inner membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Mrps2 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • mitochondrial translation

Cellular Component

Where in the cell the gene product is active
  • mitochondrial matrix
  • mitochondrion
  • mitochondrial small ribosomal subunit
  • mitochondrial inner membrane

Molecular Function

What the gene product does at the molecular level
  • structural constituent of ribosome

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.