Muc3 Gene Summary [Mouse]
Predicted to enable PDZ domain binding activity. Located in apical plasma membrane and microvillus. Is expressed in bladder; gut; hindgut; testis; and ureter. Orthologous to human MUC17 (mucin 17, cell surface associated). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Muc3 |
| Official Name | mucin 3, intestinal [Source:MGI Symbol;Acc:MGI:1203527] |
| Ensembl ID | ENSMUSG00000037390 |
| Bio databases IDs | |
| Aliases | mucin 3, intestinal |
| Synonyms | LOC100504874, MUC-3, Muc3a, mucin 17, cell surface associated |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Muc3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Family of unknown function (DUF5585)
- SEA domain
- protein binding
- PDZ-domain binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- Golgi lumen
- plasma membrane extracellular face
- apical membrane
- microvilli
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Muc3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cellular homeostasis
Cellular Component
Where in the cell the gene product is active
- external side of plasma membrane
- extracellular region
- Golgi lumen
- apical plasma membrane
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- PDZ domain binding
- extracellular matrix constituent, lubricant activity