Vopp1 Gene Summary [Mouse]
Predicted to enable enzyme binding activity. Predicted to be located in cytoplasmic vesicle membrane; late endosome; and lysosome. Predicted to be active in organelle membrane. Is expressed in several structures, including alimentary system; cardiovascular system; central nervous system; genitourinary system; and neural retina. Orthologous to human VOPP1 (VOPP1 WW domain binding protein). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Vopp1 |
| Official Name | vesicular, overexpressed in cancer, prosurvival protein 1 [Source:MGI Symbol;Acc:MGI:2141658] |
| Ensembl ID | ENSMUSG00000037788 |
| Bio databases IDs | |
| Aliases | vesicular, overexpressed in cancer, prosurvival protein 1 |
| Synonyms | ECOP, GASP, LOC691236, RGD1306494, vesicular, overexpressed in cancer, prosurvival protein 1, VOPP1 WW domain binding protein, WBP1L2 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Vopp1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- enzyme binding
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- cytoplasmic vesicle membrane
- perinuclear region
- cellular membrane
- endosomes
- lysosome
- late endosomes
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Vopp1 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- late endosome membrane
- cytoplasmic vesicle membrane
- endosome
- late endosome
- organelle membrane
- lysosomal membrane
- lysosome
Molecular Function
What the gene product does at the molecular level
- protein binding
- enzyme binding