VOPP1 Gene Summary [Human]
Located in cytoplasmic vesicle membrane and endosome. Is integral component of organelle membrane. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Processed Transcript |
| Official Symbol | VOPP1 |
| Official Name | VOPP1 WW domain binding protein [Source:HGNC Symbol;Acc:HGNC:34518] |
| Ensembl ID | ENSG00000154978 |
| Bio databases IDs | |
| Aliases | VOPP1 WW domain binding protein, Glioblastoma-amplified secreted protein, EGFR-coamplified and overexpressed protein |
| Synonyms | ECOP, GASP, LOC691236, RGD1306494, vesicular, overexpressed in cancer, prosurvival protein 1, VOPP1 WW domain binding protein, WBP1L2 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human VOPP1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- enzyme binding
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- cytoplasmic vesicle membrane
- perinuclear region
- cellular membrane
- endosomes
- lysosome
- late endosomes
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human VOPP1 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- late endosome membrane
- cytoplasmic vesicle membrane
- endosome
- late endosome
- organelle membrane
- lysosomal membrane
- lysosome
Molecular Function
What the gene product does at the molecular level
- protein binding
- enzyme binding