Sycp2l Gene Summary [Mouse]

Acts upstream of or within negative regulation of programmed cell death. Located in condensed chromosome, centromeric region; female germ cell nucleus; and lateral element. Is expressed in ovary. Orthologous to human SYCP2L (synaptonemal complex protein 2 like). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Sycp2l
Official Name
synaptonemal complex protein 2-like [Source:MGI Symbol;Acc:MGI:2685114]
Ensembl ID
ENSMUSG00000038651
Bio databases IDs NCBI: 637277 Ensembl: ENSMUSG00000038651
Aliases synaptonemal complex protein 2-like
Synonyms AABR07027258.1, C6orf177, dJ62D2.1, EG621792, Gm268, Gm40956, LOC102638754, LOC108348546, LOC682504, NO145, POF24, RGD1564922, synaptonemal complex protein 2-like
Species
Mouse, Mus musculus
OrthologiesHuman

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Sycp2l often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Synaptonemal complex 2 armadillo-repeat-like domain
  • Synaptonemal complex 2 Spt16M-like domain

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • idiopathic scoliosis
  • antiphospholipid syndrome
  • allergic rhinitis
  • vertigo
role in cell
  • apoptosis
  • number

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • nucleoplasm
  • centromeres
  • synaptonemal complexes

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Sycp2l gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • G1 phase of mitotic cell cycle
  • negative regulation of programmed cell death

Cellular Component

Where in the cell the gene product is active
  • female germ cell nucleus
  • condensed chromosome, centromeric region
  • lateral element
  • nucleoplasm

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.