SYCP2L Gene Summary [Human]

Predicted to be involved in meiotic nuclear division. Predicted to act upstream of or within negative regulation of cell death. Located in condensed chromosome, centromeric region and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Nonsense Mediated Decay
Official Symbol
SYCP2L
Official Name
synaptonemal complex protein 2 like [Source:HGNC Symbol;Acc:HGNC:21537]
Ensembl ID
ENSG00000153157
Bio databases IDs NCBI: 221711 Ensembl: ENSG00000153157
Aliases synaptonemal complex protein 2 like
Synonyms AABR07027258.1, C6orf177, dJ62D2.1, EG621792, Gm268, Gm40956, LOC102638754, LOC108348546, LOC682504, NO145, POF24, RGD1564922, synaptonemal complex protein 2-like
Species
Human, Homo sapiens
OrthologiesMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human SYCP2L often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Synaptonemal complex 2 armadillo-repeat-like domain
  • Synaptonemal complex 2 Spt16M-like domain

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • idiopathic scoliosis
  • antiphospholipid syndrome
  • allergic rhinitis
  • vertigo
role in cell
  • apoptosis
  • number

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • nucleoplasm
  • centromeres
  • synaptonemal complexes

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human SYCP2L gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • G1 phase of mitotic cell cycle
  • negative regulation of programmed cell death

Cellular Component

Where in the cell the gene product is active
  • female germ cell nucleus
  • condensed chromosome, centromeric region
  • lateral element
  • nucleoplasm

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.