Timm8b Gene Summary [Mouse]
Predicted to enable metal ion binding activity. Predicted to be involved in protein transport. Located in mitochondrion. Is expressed in several structures, including central nervous system; genitourinary system; nasal cavity epithelium; thymus primordium; and tooth. Orthologous to human TIMM8B (translocase of inner mitochondrial membrane 8 homolog B). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Timm8b |
| Official Name | translocase of inner mitochondrial membrane 8B [Source:MGI Symbol;Acc:MGI:1353424] |
| Ensembl ID | ENSMUSG00000039016 |
| Bio databases IDs | |
| Aliases | translocase of inner mitochondrial membrane 8B |
| Synonyms | DDP2, TIM8B, translocase of inner mitochondrial membrane 8B, translocase of inner mitochondrial membrane 8 homolog B |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Timm8b often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- zinc ion binding
- coiled-coil domain
- Tim10/DDP family zinc finger
- transporter
Pathways
Biological processes and signaling networks where the Timm8b gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria
- mitochondrial inner membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Timm8b gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- protein targeting to mitochondrion
- sensory perception of sound
- protein import into mitochondrial inner membrane
Cellular Component
Where in the cell the gene product is active
- extracellular space
- mitochondrial intermembrane space
- mitochondrial intermembrane space protein transporter complex
- mitochondrial inner membrane
Molecular Function
What the gene product does at the molecular level
- zinc ion binding