Ino80d Gene Summary [Mouse]

Involved in positive regulation of DNA metabolic process; regulation of embryonic development; and telomere maintenance. Predicted to be part of Ino80 complex. Predicted to be active in nucleus. Is expressed in several structures, including endocrine gland; gallbladder; genitourinary system; nervous system; and skeletal muscle tissue. Orthologous to human INO80D (INO80 complex subunit D). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Nonsense Mediated Decay
Official Symbol
Ino80d
Official Name
INO80 complex subunit D [Source:MGI Symbol;Acc:MGI:3027003]
Ensembl ID
ENSMUSG00000040865
Bio databases IDs NCBI: 227195 Ensembl: ENSMUSG00000040865
Aliases INO80 complex subunit D
Synonyms 7330405I11, A430093A21Rik, INO80 complex subunit D, RGD1304808
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ino80d often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Potential DNA-binding domain

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • Huntington disease
role in cell
  • maintenance
  • organization
  • remodeling
  • cell cycle progression

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • nucleoplasm

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Ino80d gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • positive regulation of DNA repair
  • DNA repair
  • regulation of chromosome organization
  • regulation of DNA strand elongation
  • regulation of DNA repair
  • DNA recombination
  • regulation of embryonic development
  • telomere maintenance
  • regulation of DNA replication
  • chromatin remodeling
  • positive regulation of transcription, DNA-dependent
  • regulation of cell cycle

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • Ino80 complex
  • nucleoplasm

Gene-Specific Assays for Results You Can Trust

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