Fam117b Gene Summary [Mouse]
Is expressed in cerebral cortex ventricular layer and cortical plate. Orthologous to human FAM117B (family with sequence similarity 117 member B). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Fam117b |
| Official Name | family with sequence similarity 117, member B [Source:MGI Symbol;Acc:MGI:1920000] |
| Ensembl ID | ENSMUSG00000041040 |
| Bio databases IDs | |
| Aliases | family with sequence similarity 117, member B |
| Synonyms | 2810425F24RIK, 6330416D14Rik, ALS2CR13, family with sequence similarity 117 member B, family with sequence similarity 117, member B, FLJ38771, Mapk11 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Fam117b often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- ETGE motif
- protein binding
- Protein Family FAM117
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- gastric cancer
- myocardial infarction
- sarcoidosis
- endometriosis
- vascular dementia
regulated by
- EGLN
- mir-122 (includes others)
- dimethyl n-oxalyl-glycine
role in cell
- expression in
- binding in
- growth
- 5-fluorouracil resistance
- oxaliplatin resistance
- degradation in
- ubiquitination in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Fam117b gene, providing context for its role in the cell.
Molecular Function
What the gene product does at the molecular level
- protein binding