Mmp1b Gene Summary [Mouse]

This gene encodes a member of the matrix metalloproteinase family of extracellular matrix-degrading enzymes that are involved in tissue remodeling, wound repair, progression of atherosclerosis and tumor invasion. The encoded preproprotein undergoes proteolytic processing to generate a mature, zinc-dependent endopeptidase enzyme. This gene is located in a cluster of other matrix metalloproteinase genes on chromosome 9. [provided by RefSeq, Feb 2016]

Details

Type
Protein Coding
Official Symbol
Mmp1b
Official Name
matrix metallopeptidase 1b (interstitial collagenase) [Source:MGI Symbol;Acc:MGI:1933847]
Ensembl ID
ENSMUSG00000041620
Bio databases IDs NCBI: 83996 Ensembl: ENSMUSG00000041620
Aliases matrix metallopeptidase 1b (interstitial collagenase)
Synonyms LOC100910997, matrix metallopeptidase 1b (interstitial collagenase), Mcol-B
Species
Mouse, Mus musculus
OrthologiesRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Mmp1b often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Putative peptidoglycan binding domain
  • Matrixin
  • Hemopexin-like repeats
  • ZnMc
  • endopeptidase
  • peptidase
  • HX
  • Zinc-dependent metalloprotease
  • metalloendopeptidase

Pathways

Biological processes and signaling networks where the Mmp1b gene in mouse plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Unknown

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.