Slc16a6 Gene Summary [Mouse]
Predicted to enable monocarboxylic acid transmembrane transporter activity. Predicted to be involved in taurine transmembrane transport. Predicted to be located in basolateral plasma membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including central nervous system; integumental system; liver; retina; and urinary system. Orthologous to human SLC16A6 (solute carrier family 16 member 6). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Slc16a6 |
| Official Name | solute carrier family 16 (monocarboxylic acid transporters), member 6 [Source:MGI Symbol;Acc:MGI:2144585] |
| Ensembl ID | ENSMUSG00000041920 |
| Bio databases IDs | |
| Aliases | solute carrier family 16 (monocarboxylic acid transporters), member 6 |
| Synonyms | ESTM12, MCT 6, MCT 7, Mct7B, solute carrier family 16 member 6, solute carrier family 16, member 6, solute carrier family 16 (monocarboxylic acid transporters), member 6 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Slc16a6 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- taurine transporter
- Multidrug resistance protein
- Major Facilitator Superfamily
- drug resistance transporter, EmrB/QacA subfamily
- protein binding
- monocarboxylic acid transporter
- monocarboxylate transporter 1
- transporter
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulates
- monocarboxylic acid
disease
- ischemic stroke
- Marfan syndrome
- diabetes mellitus
- cervical cancer
- primary pulmonary hypertension
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cellular membrane
- basolateral membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Slc16a6 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- monocarboxylic acid transport
- taurine transport
Cellular Component
Where in the cell the gene product is active
- membrane
- basolateral plasma membrane
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- taurine transmembrane transporter activity
- monocarboxylic acid transmembrane transporter activity