Aqp6 Gene Summary [Mouse]
Predicted to enable carbon dioxide transmembrane transporter activity; channel activity; and nitrate transmembrane transporter activity. Predicted to be involved in carbon dioxide transport; nitrate transmembrane transport; and renal water transport. Predicted to act upstream of or within water transport. Predicted to be located in cytoplasmic vesicle membrane. Is expressed in cecum; early conceptus; gonad; and metanephros. Orthologous to human AQP6 (aquaporin 6). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Aqp6 |
| Official Name | aquaporin 6 [Source:MGI Symbol;Acc:MGI:1341204] |
| Ensembl ID | ENSMUSG00000043144 |
| Bio databases IDs | |
| Aliases | aquaporin 6 |
| Synonyms | AI790337, AQP2L, Aquaporin-2-like, aquaporin 6, KID |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Aqp6 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- nitrate transporter
- anion channel
- MIP
- chloride channel
- ligand-gated ion channel
- protein binding
- water channel
- ammonium transporter
- transporter
Pathways
Biological processes and signaling networks where the Aqp6 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- membrane fraction
- cytoplasmic vesicle membrane
- intracellular membranes
- cellular membrane
- Plasma Membrane
- vesicles
- pedicels
- Golgi cisternae
- perikaryon
- vesicle fraction
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Aqp6 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- water transport
- carbon dioxide transport
- nitrate transport
- renal water transport
- odontogenesis
Cellular Component
Where in the cell the gene product is active
- cytoplasmic vesicle membrane
- apical plasma membrane
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- nitrate transmembrane transporter activity
- protein binding
- water channel activity