Pxylp1 Gene Summary [Mouse]
Predicted to enable phosphatase activity. Predicted to be involved in chondroitin sulfate proteoglycan biosynthetic process and positive regulation of heparan sulfate proteoglycan biosynthetic process. Predicted to be located in Golgi membrane. Predicted to be active in Golgi apparatus. Is expressed in central nervous system; jaw; musculoskeletal system; and olfactory epithelium. Orthologous to human PXYLP1 (2-phosphoxylose phosphatase 1). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Pxylp1 |
| Official Name | 2-phosphoxylose phosphatase 1 [Source:MGI Symbol;Acc:MGI:2442444] |
| Ensembl ID | ENSMUSG00000043587 |
| Bio databases IDs | |
| Aliases | 2-phosphoxylose phosphatase 1 |
| Synonyms | 2-phosphoxylose phosphatase 1, 9430094M07RIK, ACPL2, BB177120, C130099A20Rik, HEL124, XYLP |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Pxylp1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- acid phosphatase
- phosphatase
- Histidine phosphatase superfamily (branch 2)
- protein binding
- Histidine phosphatase domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Golgi Apparatus
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Pxylp1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- chondroitin sulfate proteoglycan biosynthetic process
- glycosaminoglycan biosynthetic process
- dephosphorylation
- positive regulation of heparan sulfate proteoglycan biosynthetic process
Cellular Component
Where in the cell the gene product is active
- Golgi membrane
- Golgi apparatus
Molecular Function
What the gene product does at the molecular level
- protein binding
- phosphatase activity