PXYLP1 Gene Summary [Human]

Enables phosphatase activity. Involved in chondroitin sulfate proteoglycan biosynthetic process; glycosaminoglycan biosynthetic process; and positive regulation of heparan sulfate proteoglycan biosynthetic process. Located in Golgi apparatus. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
PXYLP1
Official Name
2-phosphoxylose phosphatase 1 [Source:HGNC Symbol;Acc:HGNC:26303]
Ensembl ID
ENSG00000155893
Bio databases IDs NCBI: 92370 Ensembl: ENSG00000155893
Aliases 2-phosphoxylose phosphatase 1
Synonyms 2-phosphoxylose phosphatase 1, 9430094M07RIK, ACPL2, BB177120, C130099A20Rik, HEL124, XYLP
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human PXYLP1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • acid phosphatase
  • phosphatase
  • Histidine phosphatase superfamily (branch 2)
  • protein binding
  • Histidine phosphatase domain

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • dementia
regulated by
regulates
  • chondroitin sulfate proteoglycan
  • glycosaminoglycan
  • heparan sulfate proteoglycan

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Golgi Apparatus

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human PXYLP1 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • chondroitin sulfate proteoglycan biosynthetic process
  • glycosaminoglycan biosynthetic process
  • dephosphorylation
  • positive regulation of heparan sulfate proteoglycan biosynthetic process

Cellular Component

Where in the cell the gene product is active
  • Golgi membrane
  • Golgi apparatus

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • phosphatase activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.