Bclaf3 Gene Summary [Mouse]
Predicted to enable DNA binding activity and transcription coregulator activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to be located in mitochondrion. Predicted to be part of mediator complex. Is expressed in central nervous system and retina. Orthologous to human BCLAF3 (BCLAF1 and THRAP3 family member 3). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Bclaf3 |
| Official Name | Bclaf1 and Thrap3 family member 3 [Source:MGI Symbol;Acc:MGI:2685992] |
| Ensembl ID | ENSMUSG00000044150 |
| Bio databases IDs | |
| Aliases | Bclaf1 and Thrap3 family member 3 |
| Synonyms | 2310067E24Rik, A830080D01Rik, BCLAF1 and THRAP3 family member 3, CXorf23, Gm1146, LOC108349218, RGD1562161 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Bclaf3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- THRAP3/BCLAF1 family
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Bclaf3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- positive regulation of transcription from RNA polymerase II promoter
Cellular Component
Where in the cell the gene product is active
- mediator complex
- mitochondrion
Molecular Function
What the gene product does at the molecular level
- DNA binding
- transcription cofactor activity