Erh Gene Summary [Mouse]
Predicted to enable methyl-CpG binding activity. Involved in osteoblast differentiation. Located in membrane. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human ERH (ERH mRNA splicing and mitosis factor). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Erh |
| Official Name | ERH mRNA splicing and mitosis factor [Source:MGI Symbol;Acc:MGI:108089] |
| Ensembl ID | ENSMUSG00000021131 |
| Bio databases IDs | |
| Aliases | ERH mRNA splicing and mitosis factor |
| Synonyms | DROER, ERH mRNA splicing and mitosis factor, ERH, mRNA splicing and mitosis factor, LOC678886, Mer, PREI1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Erh often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- methyl-CpG binding
- Enhancer of rudimentary
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- rheumatoid arthritis
- intrahepatic cholestasis of pregnancy
regulates
- pyrimidine nucleoside
- SOCS3
- nucleic acid component or derivative
role in cell
- expression in
- morphology
- regulation in
- regulation
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- interchromatin granule cluster fractions
- midbody
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Erh gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- nucleobase-containing compound metabolic process
- pyrimidine nucleoside metabolic process
Cellular Component
Where in the cell the gene product is active
- nucleus
- methylosome
- midbody
Molecular Function
What the gene product does at the molecular level
- protein binding
- RNA binding
- methyl-CpG binding