Nxph1 Gene Summary [Mouse]
Enables signaling receptor binding activity. Involved in modulation of chemical synaptic transmission. Is active in GABA-ergic synapse; glutamatergic synapse; and synaptic cleft. Is expressed in brain; metanephros; and spinal cord mantle layer. Orthologous to human NXPH1 (neurexophilin 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Processed Transcript |
| Official Symbol | Nxph1 |
| Official Name | neurexophilin 1 [Source:MGI Symbol;Acc:MGI:107492] |
| Ensembl ID | ENSMUSG00000046178 |
| Bio databases IDs | |
| Aliases | neurexophilin 1 |
| Synonyms | C130005L03Rik, Nbla00697, neurexophilin 1, NPH1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Nxph1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Neurexophilin
- receptor binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- glutaminergic synapse
- synapse
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Nxph1 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- extracellular region
Molecular Function
What the gene product does at the molecular level
- receptor binding